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KMID : 0357219990110020131
Journal of Korean Society Physical Therapy
1999 Volume.11 No. 2 p.131 ~ p.137
Neurotrophic Factors and Their Roles


Abstract
Neurotrophic factors control the survival and differentiation in developing neurons, Furthermore, nut evidence suggests that neurotrophic factors promote the axonal growth and synaptic plasticity In the CNS. Research is currently being undertaken in order to determine whether members of the neurotrophic factor family have potential therapeutic roles in preventing and/or reducing the neuronal cell death and atrophy. This review summarizes the current knowledge of characterized neurotrophic factors including NGF, BDNF, NT-3, and NT-4/5.
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